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God’s Red Pencil? CRISPR and The Three Myths of Precise Genome Editing

crispr-cas9

by Jonathan Latham, PhD

For the benefit of those parts of the world where public acceptance of biotechnology is incomplete, a public relations blitz is at full tilt. It concerns an emerging set of methods for altering the DNA of living organisms. “Easy DNA Editing Will Remake the World. Buckle Up; “We Have the Technology to Destroy All Zika Mosquitoes“; and “CRISPR: gene editing is just the beginning”. (CRISPR is short for CRISPR/cas9, which is short for Clustered Regularly-Interspaced Short Palindromic Repeats/CRISPR associated protein 9; Jinek et al., 2012. It is a combination of a guide RNA and a protein that can cut DNA.) … Continue Reading

The Experiment Is on Us: Science of Animal Testing Thrown into Doubt

by Pat Dutt and Jonathan Latham, PhD

New scientific research has cast grave doubt on the safety testing of hundreds of thousands of consumer products, food additives and industrial chemicals.

Everyday products, from soft drinks and baby foods, to paints, gardening products, cosmetics and shampoos, contain numerous synthetic chemicals as preservatives, dyes, active ingredients, or as contaminants. Official assurances of the safety of these chemicals are based largely on animal experiments that use rabbits, mice, rats and dogs. But new results from a consortium of researchers and published in the Proceedings of the National Academy of Sciences suggest such assurances may be worthless (Seok et al. 2013). … Continue Reading

Seralini and Science: an Open Letter

Gilles-Eric Seralini

(Authors listed below) (Traduction Francaise)

A new paper by the French group of Gilles-Eric Seralini describes harmful effects on rats fed diets containing genetically modified maize (variety NK603), with and without the herbicide Roundup, as well as Roundup alone. This peer-reviewed study (Seralini et al., 2012), has been criticized by some scientists whose views have been widely reported in the popular press (Carmen, 2012; Mestel, 2012; Revkin, 2012; Worstall, 2012).  Seralini et al. (2012) extends the work of other studies demonstrating toxicity and/or endocrine-based impacts of Roundup (Gaivão et al., 2012; Kelly et al., 2010; Paganelli et al., 2010; Romano et al., 2012), as reviewed by Antoniou et al. (2010).

The Seralini publication, and resultant media attention, raise the profile of fundamental challenges faced by science in a world increasingly dominated by corporate influence. These challenges are important for all of science but are rarely discussed in scientific venues. … Continue Reading

Pew Commission Report: Industrial Animal Farming Poses “Unacceptable” Risks for Public Health and the Environment

May 4, 2008 (Un)Sustainable Farming, Health, News Comments Off on Pew Commission Report: Industrial Animal Farming Poses “Unacceptable” Risks for Public Health and the Environment

Pew Press Release is reproduced below:

The current industrial farm animal production (IFAP) system often poses unacceptable risks to public health, the environment and the welfare of the animals themselves, according to an extensive 2½-year examination conducted by the Pew Commission on Industrial Farm Animal Production (PCIFAP), in a study released today.

… Continue Reading

Study Questions Application of Animal Experiments to Humans

March 30, 2007 Health, News Comments Off on Study Questions Application of Animal Experiments to Humans

Jonathan Latham and Allison Wilson

Much of science, including healthcare research and important fields of risk assessment, depend, in part or in whole, on the presumption that animal models can usefully predict human responses to treatments. However, relatively little research has been done to test this assumption. A new study has compared the results of animal experiments and human clinical trials. The study selected six treatments in which the human clinical trials had shown a clear result (either benefit or harm). They compared these to the results of animal tests. In three cases the results were in concordance while in the other three they were not.
… Continue Reading

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Commentaries

Gene Drives: A Scientific Case for a Complete and Perpetual Ban

Mosquito and DNA

by Jonathan Latham, PhD One of the central issues of our day is how to safely manage the outputs of industrial innovation. Novel products incorporating nanotechnology, biotechnology, rare metals, microwaves, novel chemicals, and more, enter the market on a daily basis. Yet none of these products come with an adequate …

Genetics Is Giving Way to a New Science of Life

Phytoplankton

by Jonathan Latham, PhD Test your understanding of the living world with this simple question. What kind of biomolecule is found in all living organisms? If your answer is “DNA”, you are incorrect. The mistake is very forgiveable though. The standard English-language biology education casts DNA (DeoxyriboNucleic Acid) as the …

Industrial Production of Poultry Gives Rise to Deadly Strains of Bird Flu H5Nx

A factory chicken farm

by Robert G. Wallace Multiple outbreaks of deadly H5 bird flu are decimating poultry across Europe, Asia, and the Middle East. The epidemic, moving across Eurasia in wave after wave, follows an eruption of H5N2 here in the U.S. in 2015. All the new strains—H5N2, H5N3, H5N5, H5N6, H5N8, and …

There’s Nothing Parochial About the Issue of GMO Food Labeling

Monsanto Prop 37

by Jonathan Latham, PhD The GMO labeling issue has quieted down some but there is still plenty to discuss. Just this week the USDA proposed to redefine GMOs with new loopholes for gene editing. However, it is also possible for reasonable people to imagine that GMO labeling is a sideshow …

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Reviews

Poison Spring: The Secret History of Pollution and the EPA

Poison Spring Evaggelos Valllianatos

Book Author: Evaggelos Vallianatos with McKay Jenkins Reviewed by: Carol Van Strum “Science is the belief in the ignorance of experts,” Richard Feynman famously declared in 1966. Ever quick to challenge accepted wisdom, he distinguished the laudable ignorance of science, forever seeking unattainable certainties, from the dangerous ignorance of experts …

The Real Cost of Fracking: How America’s Shale Gas Boom Is Threatening Our Families, Pets, and Food

The Real Cost of Fracking book cover

Book Authors: Michelle Bamberger and Robert Oswald Reviewed by Allison Wilson (The Bioscience Resource Project) The first researchers to systematically document ill health in livestock, pets, and people living near fracking drill sites were Michelle Bamberger and Robert Oswald. Bamberger, a veterinarian, and Oswald, a professor of molecular medicine at …

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