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The Experiment Is on Us: Science of Animal Testing Thrown into Doubt

by Pat Dutt and Jonathan Latham, PhD

New scientific research has cast grave doubt on the safety testing of hundreds of thousands of consumer products, food additives and industrial chemicals.

Everyday products, from soft drinks and baby foods, to paints, gardening products, cosmetics and shampoos, contain numerous synthetic chemicals as preservatives, dyes, active ingredients, or as contaminants. Official assurances of the safety of these chemicals are based largely on animal experiments that use rabbits, mice, rats and dogs. But new results from a consortium of researchers and published in the Proceedings of the National Academy of Sciences suggest such assurances may be worthless (Seok et al. 2013). … Continue Reading

Biology as Ideology: The Doctrine of DNA

May 13, 2012 Health, Reviews Comments Off
Biology as Ideology

Author: by Richard Lewontin

ISBN: 0140232192 Publisher: Penguin books (1991)

Biologists know that complex traits are typically associated with genetic variation between individuals. Nevertheless, if we hear on the news that obesity, antisocial behaviour or some other disorder has a strong genetic component, we are likely to attach special significance to this ‘fact’. We may be less likely to attribute social factors as a cause and we may be more likely to accept a technological or pharmaceutical solution as a remedy. The disorder may also acquire a credibility and a sense of inevitability that it previously lacked. The reasoning that leads to these conclusions has a certain logic, after all we investigate causes primarily so that we can find remedies, but nevertheless we need to be careful that our thinking is well-founded.

… Continue Reading

Psychiatrists plead to continue funding of genetic approaches to disease

August 30, 2011 Health, News 5 Comments

Jonathan Latham

Ninety six leading psychiatric geneticists have publicly requested their scientific funding agencies not to abandon the search for genetic links to mental health. In a letter, published Aug 9th in the journal Molecular Psychiatry, they argue that the ongoing failure to uncover significant disease genes for mental illness does not indicate that current research is fundamentally misdirected.

Instead, they believe that current experimental designs lack sufficient statistical power. And it is a defect they want remedied by further studies. “Since family history is a major risk factor” they write “we urge the major funding bodies worldwide to continue to support GWAS (Genome-Wide Association Studies) as a major investigative tool’. … Continue Reading

23andMe disproves its own business model

July 7, 2011 Health, News 1 Comment

Jonathan Latham

Online gene testing company 23andMe last week published its first genetic research study into Parkinson’s Disease. The study was funded by the participants (many of whom are customers of 23andMe), the company itself, and Google-founder Sergei Brin, who is married to 23andMe’s CEO and founder, Anne Wojcicki (1). Wojcicki is also personally subsidising the company and is a co-author on the paper.

23andMe’s study shows that two new genes it has discovered, plus all known existing genes linked to the disease, are not much better than random selection for predicting who will get Parkinson’s Disease. … Continue Reading

The Great DNA Data Deficit: Are Genes for Disease a Mirage?

Are Genes for Disease a Mirage?

Jonathan Latham and Allison Wilson

Just before his appointment as head of the US National Institutes of Health (NIH), Francis Collins, the most prominent medical geneticist of our time, had his own genome scanned for disease susceptibility genes. He had decided, so he said, that the technology of personalised genomics was finally mature enough to yield meaningful results. Indeed, the outcome of his scan inspired The Language of Life, his recent book which urges every individual to do the same and secure their place on the personalised genomics bandwagon.

… Continue Reading

Study Questions Application of Animal Experiments to Humans

March 30, 2007 Health, News Comments Off

Jonathan Latham and Allison Wilson

Much of science, including healthcare research and important fields of risk assessment, depend, in part or in whole, on the presumption that animal models can usefully predict human responses to treatments. However, relatively little research has been done to test this assumption. A new study has compared the results of animal experiments and human clinical trials. The study selected six treatments in which the human clinical trials had shown a clear result (either benefit or harm). They compared these to the results of animal tests. In three cases the results were in concordance while in the other three they were not.
… Continue Reading

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Commentaries

Edward Snowden’s Testimony to the European Parliament on NSA Spying and its Consequences

Edward Snowden Barton Gellman/Getty Images

Independent Science News has decided to reprint (1) in full the March 7th testimony of Edward Snowden to the European Parliament. Snowden’s testimony is vitally important for every citizen in every country to understand, yet it has barely been covered by the commercial or (non-commercial) global media. At stake is the …

The Health Care Doctors Forgot: Why Ordinary Food Will Be the Future of Medicine

Apple and a Pear

by T Colin Campbell, Jacob Gould Schurman Professor Emeritus, Cornell University The problem Few issues have become so intensely debated and politically charged as the need to reform the health care system. This debate has resulted in the ObamaCare program (The Affordable Care Act), which aims to expand and improve …

Fakethrough! GMOs and the Capitulation of Science Journalism

Biotechnology

by Jonathan Latham, PhD Good journalism examines its sources critically, it takes nothing at face value, places its topics in a historical context, and it values above all the public interest. Such journalism is, most people agree, essential to any equitable and open system of government. These statements about journalism …

The Founding Fables of Industrialised Agriculture

Farming in Italy

by Colin Tudge Governments these days are not content with agriculture that merely provides good food. In line with the dogma of neoliberalism they want it to contribute as much wealth as any other industry towards the grand goal of “economic growth”. High tech offers to reconcile the two ambitions …

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Reviews

Biology as Ideology: The Doctrine of DNA

Biology as Ideology

Author: by Richard Lewontin ISBN: 0140232192 Publisher: Penguin books (1991) Biologists know that complex traits are typically associated with genetic variation between individuals. Nevertheless, if we hear on the news that obesity, antisocial behaviour or some other disorder has a strong genetic component, we are likely to attach special significance …

The Unsettling of America

The Unsettling of America

Author: Wendell Berry ISBN: 0871568772 Publisher: Sierra Club books (1977) In 2002, peasant associations from all over Asia organised an international scientific conference. The motivation for the conference was the fact that peasants and their leaders had no dialogue with agricultural scientists, either from their own countries or with those …

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